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Female Steroids

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  • Specifications
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  • COA

Product name:Gestonoronacetat / Gestonorone Acetate

CAS:31981-44-9

Synonyms:17-Hydroxy-19-norpregn-4-ene-3,20-dione 17-acetate;17alpha-Hydroxy-19-norprogesterone-17alpha acetate;19-Nor-17alpha-hydroxyprogesterone acetate,Norhydroxyprogesterone Acetate

Molecular Formula:C22H30O4

Molecular Weight:358.47

EINECS No.:250-882-8

Density:1.16g/cm3

Melting point:228-230℃

Gestonorone acetate, or gestronol acetate, also known as norhydroxyprogesterone acetate, is a progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups which was developed in the early 1960s but was never marketed.

Gestonorone acetate has been found to consistently inhibit ovulation at an oral dosage of 10 mg/day in combination with 50 μg/day oral ethinylestradiol.Weak or no endometrial effects were observed at an oral dosage of 100 mg/day, basal vacuoles appeared at 130 to 140 mg/day, and full endometrial secretory transformation occurred at 220 mg/day.

TEST ITEMS SPECIFICATION RESULTS
Description White or Almost White Crystalline Powder white powder
Identification A.B. Positive
Assay 97.0~103.0% 99.1%
Loss On Drying 1.0%max 0.25%
Melting Point 222~228°C 227°C
Organic Volatile Impurities meets the requirement. Conforms
Related Substances meets the requirement. Conforms
Residual Solvents meets the requirement. Conforms
Particle Size 100%20 microns Conforms
Conclusion The specification conform with USP30 standard

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