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アクティブ医薬品

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商品名 Ethacridine Lactate Monohydrate / リバノール
キャス番号 6402-23-9
分子式 C15H15N3O.C3H6O3.H2O
分子量 361.4
外観 yellow powder
融点 243-245 ℃(点灯。)

Rivanol is the lactate-hydrate of α-ethoxy-6,9-diaminoacridine. It is a bactericidal preservative for external use and has a strong killing effect on gram-positive bacteria and a few gram-negative bacteria. , Has good antibacterial effect on cocci, especially streptococcus, and has strong activity in alkaline environment. This product is small in irritation, and the therapeutic concentration does not damage the general tissues, but it can stimulate the contraction of uterine smooth muscle, soften and relax the cervix. したがって, it can be used to induce labor in women's mid-term pregnancy without obvious side effects.

1. Disinfection: Ethacridine Lactate Monohydrate is a disinfectant and antiseptic that inhibits the growth of Gram-positive bacteria, especially cocci. The solution can be used for the disinfection of small, lightly traumatised wounds and infected wounds. It can cause burning sensation, allergy, rash, itching and other adverse reactions.

2. Bactericidal: Ethacridine Lactate Monohydrate is disinfectant and bactericidal and can be used externally as a cream to disinfect small wounds on the skin surface. Occasionally there are allergic reactions.

3. Induction of labour in mid pregnancy: Ethacridine Lactate Monohydrate Injection is commonly used to induce labour in mid pregnancy by injecting a concentration into the amniotic cavity to cause sterile inflammation, stimulate uterine contractions and expel the foetus.

ITEM SPECIFICATION RESULTS
Description Yellow crystalline powder; odourless

Soluble in hot water, soluble in boiling anhydrous ethanol, 水にわずかに溶ける, slightly soluble in ethanol, insoluble in ether

準拠
識別 Consistent with the

Pharmacopoeia (1,2,3,4)

準拠
PH 6.0-7.0 準拠
Chloride(Cl) The general principles of the pharmacopoeia 0801 準拠
Sulfate(SO4) The general principles of the

pharmacopoeia 0802

準拠
Related substance The general principles of the

pharmacopoeia 0512

準拠
乾燥減量 The general principles of the pharmacopoeia 0831

4.5%-5.5%

準拠
ignition residue The general principles of the pharmacopoeia 0841

≤0.1%

0.08%
ヘビーメタル The general principles of the pharmacopoeia 0821

≤30ppm

準拠
アッセイ The general principles of the pharmacopoeia 0710 99.3%
結論 Conform to Chinese Pharmacopoeia 2015

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