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Produktnavn: Vinblastine sulfate
Synonymer: 29060le;exal;nsc49842;rozevinsulfate;velban;velbe;vincaleukoblastine,sulfate(1:1)(salt);Vinblastine, sulphate salt
CAS: 143-67-9
MF: C46H60N4O13S
MW: 909.05
EINECS: 205-606-0

Vinblastine is a medication used to treat a number of types of cancer including: Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, and testicular cancer among others.It is used intravenously and works by inhibiting mitosis.

1. It has vasodilating, blood thinning, and memory-enhancing actions.

2. It acts as a cerebral stimulant and vasodilator.

3. It is used to treat arteriosclerosis.

4. It is very effective in curing dementia caused due to insufficient blood supply to the brain.

5. It interferes with cells' ability to synthesize DNA and RNA.

Mainly used for the treatment of solid tumor. For malignant lymphoma, testicular neoplasm and choriocarcinoma curative effect is better. For lung, breast, ovarian, skin cancer, renal mother cell tumor and monocytes leukaemia also have certain curative effect.

Varer Standarder Resultater
Utseende White or off-white solid powder Overholder
Identifikasjon By IR Overholder
By HPLC Overholder
Løselighet Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, uløselig i vann Overholder
Polymorphic Form Polymorphic form 1 Overholder
Smeltepunkt 211ºC~216ºC 212.8ºC~214.9ºC
Vanninnhold ≤ 0.50% 0.10%
Tungmetaller ≤ 20ppm Overholder
Residue on Ignition ≤ 0.20% 0.09%
Related Substance Any single impurity: ≤0.10% 0.06%
Total Impurities: ≤1.00% 0.16%
Assay (on the anhydrous basis) 98.0%~102,0 % 99.94%
Particle Size D90: ≤100µm Overholder
Reference Standard In-house Standard
Konklusjon The product complied to In-house standard.

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