1. Nome do Produto: 2 – (diethylamino) – N – (2 minus 2 – trimethylphenyl) acetamidemonohydrochloride
2. Product nicknames :Acetamide,2-(dimethylamino-n -(2,4,6-trimethylphenyl)-, Acetamide,2-(dimethylamino-n -) (2,4,6-trimethylphenyl)-, Acetamide (1:1); TrimecaineHCl2 – (diethylamino) – N – (2 minus 2 – trimethylphenyl) acetamidemonohydrochloride; 2 – (diethylamino) – N – (2 minus 2 – trimethylphenyl) acetamidemonohydrochloride; TrimecaineCl (MesocaineCl); Mesidicainehydrochloride; Mesocainehydrochloride; Trimecainehydrochloride; Trimecaine · HCl (Mesocaine · HCl)
3. CAS no. : 1027-14-1
4. Fórmula molecular: C15H25ClN2O
5. Peso molecular: 284.8248
6. EINECS no. : 213-836-8
7. Ponto de fusão :137-138℃ (acetone)
8. Vapor pressure: 2.24E-05mmHg a 25°C
Trimecaine HCl is an organic compound used as a local anesthetic and as an antiarrhythmic drug. White crystalline powder soluble in water and ethanol. It is the product Mesdicain, Mesocain, Mesokain and other products in the active ingredients.
A local anesthetic and cardial antiarrhythmic. It used in epidural postoperative analgesia after major urological procedures in combination with morpine.
[Alias] Trifecaine hydrochloride, Trimecaine Hydrochlortde, Mesidicaine Hydrochliride.
[Properties] for the white needle-like crystal or crystalline powder; odorless, bitter and numb. Soluble in water and hot ethanol, slightly soluble in alcohol, insoluble in chlorofrm and so on.
[Role and use] for the amide type local anesthetic, anesthetic effect than procaine and lidocaine strong, play a role fast. Infiltration anesthesia and conduction anesthesia after l 1.5 minutes after the emergence of anesthesia, the role of a long time, can be maintained for about 3 hours, the wound around the analgesic effect can be maintained for 8-12 hours. For infiltration anesthesia, conduction anesthesia and epidural anesthesia.
[Usage and dosage] infiltration anesthesia: 0,125-1% off the physiological saline solution, the largest amount of 1% solution can be used to 100ml, 0.5% solution can be used to 500ml, nerve block drunk: 1-2% solução, 1 % Solution from March to 100ml, 2% solution available 20ml, the solution can be added a small amount of epinehrine hydrochloride to increase the durability and reduce the absorption of toxicity.
[Note] toxicity than procaine hydrochloride, lidocaine hydrochloride and tetracaine hydrochloride small.
[Armazenar] dark, sealed.
[Especificação] Injection: Each 20ml: O. 4g.
Trimecaine HCl has two main applications. The first is local anesthesia (local, osmotic, local mucosa and inhalation, spinal cord and Bier vein). In the mixture with , its concentration is 0.4 para 4%, and in some cases (for example, in dentistry). Another area is the prevention and treatment of arrhythmias in myocardial infarction and cardiac surgery. It is also used for the prevention of sympathetic reactions during tracheal intubation.
