State: Pevné
Vzorec: C26H29NO
Used for: Kulturistika
Číslo CAS: 10540-29-1
Molárna hmota: 371.515 g/mol
Biological Half-Life: 5-7 dni
Trade Names: Genox, Tamifen, others
Vzhľad: Biely kryštalický prášok
Nolvadex is the name of the drug whose scientific name is tamoxifen citrate. Nolvadex is not a steroid - it is a potent anti-estrogen used as an ancillary drug during cycle when symptoms of gyno occur. It can also be used post cycle to restore natural testosterone production. Symptoms of gyno can occur when using a cycle which contains drugs which aromatize, including (but not limited to) testosterones such as enanthate, cypionate, and suspension. The drug is an estrogen agonist/antagonist, which binds to estrogen receptors in different tissues. Whether nolvadex acts as an estrogen agonist or antagonist depends on which type of tissue it is working in. When the tamoxifen molecule binds to the receptors, estrogen is blocked and cannot result in any type of action - therefore an anti-estrogen effect is exhibited. Nolvadex is used clinically in the treatment of breast cancer since many forms of breast cancer are responsive to the action of estrogen. Nolvadex blocks its actions and works as an effective treatment. Aside from direct treatment of breast cancer, it is used as a preventative measure for those with a genetic predisposition for breast cancer. While nolvadex is likely the most popular on-cycle anti-estrogen due to its affordable price, more potent remedies are available such as arimidex, femara, and aromasin. These ancillary drugs prevent estrogen from being manufactured in the first place and make gyno related side effects virtually nonexistent.
Nolvadex is used for treating breast cancer that has spread to other sites in the body. It is also used along with other medicines to treat other types of breast cancer. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation) to decrease the risk of developing breast cancer. It may also be used for other conditions as determined by your doctor. Nolvadex is an anti-estrogen. It works by blocking the effect of estrogen on certain tumors. This may prevent the growth of tumors that are activated by estrogen.
