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Lokale anesthetica

» Geneesmiddelen » Lokale anesthetica

  • Specificaties:
  • product beschrijving
  • Productgebruik:
  • COA
productnaam Procaine
CAS 59-46-1
Zuiverheid 99%
MF C13H20N2O2
MW 236.31
Uiterlijk wit poeder
Opslag Schaduw,beperkte bewaring
Origion of Place China

Procaine is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.

Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In aanvulling, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.

Test Items Specificatie Test Results
Uiterlijk White crystals or a white crystalline powder Conform
Identificatie ABE. It appears positive reaction
Smeltpunt 154degree~158degree 154degree~157degree
Acidity PH 5.0~6.5 PH=5.9
Appearance of solution Clear and colourless Conform
Verlies bij drogen ≤0,5% 0.07%
Heavy metals ≤0.0005% Conform
Gerelateerde substanties ≤0.05% Conform
Sulphated ash ≤0.1% 0.05%
Assay ( on dry basis ) 99.0-101.0% 99.87%
Conclusion Conform to BP2005

 

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