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Peptide farmaceutice

» Peptide » Peptide farmaceutice

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numele produsului:Acetat de pramlintidă

Alt nume:amilină (Uman),Symlin

CAS:196078-30-5

MF:C173H273N51O56S2

MW:4027.46

MP:>175°C

Pramlintide acetate is an injectable human amylin analog that has been launched for the treatment of both type 1 and type 2 Diabet, in conjunction with insulin. While it is also a 37-amino acid peptide, it differs from its parent predecessor by the substitution of Ala-25, Ser-28, and Ser-29 with prolines. Not only do these modifications improve the solubility of the peptide, they also eliminate the aggregation observed with amylin, resulting in a stable synthetic analog with retention of biological activity that is suitable for pharmaceutical use.

Symlin (pramlintide acetate) is a prescription medicine used to treat the symptoms of Type 1 and Type 2 Diabetes. Symlin may be used alone or with other medications.

Symlin belongs to a class of drugs called Antidiabetics, Amylinomimetics.It is not known if Symlin is safe and effective in children.

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