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Farmaceutice active

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numele produsului: Methylprednisolone
Sinonime: (6alfa,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;11,17,21-trihydroxy-6-methyl-1,4-pregnadiene-3,20-dione;11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione;1-dehydro-6alpha-methylhydrocortisone;20-dione,11,17,21-trihydroxy-6-methyl-,(6alfa,11beta)-pregna-4-diene-3;20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-4-diene-3;20-dione,11beta,17,21-trihydroxy-6alpha-methyl-pregna-4-diene-3
CAS: 83-43-2
MF: C22H30O5
MW: 374.47
EINECS: 201-476-4
Categorii de produse: Miscellaneous Biochemicals;Biochimie;Hidroxicetosteroizi;Steroizi;Intermediari & Produse chimice fine;Produse farmaceutice;Steroid and Hormone;API;MEDROL;Hormone Drugs
Densitate: 1.28 g/cm3
Punct de topire: 228-237 °C (dec.)
Punct de fierbere: 571.8 °C la 760 mmHg
Punct de aprindere: 313.7 °C
Aspect: White to off-white crystalline powder

Methylprednisolone is one kind of white to off-white crystalline powder. And its IUPAC name is also called(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[A]phenanthren-3-one. It belongs to the classes of Miscellaneous Biochemicals; Biochimie; Hidroxicetosteroizi; Steroizi; Intermediari & Produse chimice fine; Produse farmaceutice. It is sparingly soluble in alcohol, in dioxane, and in methanol, slightly soluble in acetone, and in chloroform, and very slightly soluble in ether. It is practically insoluble in water.

Methylprednisolone provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, artrită, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Methylprednisolone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

The Classification Code of this chemical is Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-inflammatory; Antiemetics; Autonomic Agents; Central Nervous System Agents; Drug / Therapeutic Agent; Gastrointestinal Agents; Glucocorticoid; Glucocorticoids; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Immunosuppressant; Neuroprotective agents; Peripheral Nervous System Agents; Protective Agents.

Methylprednisolon e has a strong anti-inflammatory effect and a weak sodium retention effect. Its anti-inflammatory effect is 7 times that of cortisone; methylprednisolon e succinate sodium is a water-soluble prednisolon e derivative, which is transformed in the body It is methylprednisolon e, which can be injected, has a quick-acting effect, and has a medium maintenance time. It is the preferred medicine for the treatment of inflammation and allergies. Acetate is a suspension, which has a slow onset and lasting effect after injection. Methylprednisolon e is a moderately effective glucocorticoid. The effect is the same as that of prednisolon e, its anti-inflammatory effect is 3 times that of the latter, the glucose metabolism effect is 10 times stronger than that of hydrocortisone, and the water and sodium retention effect is weak, and there is no side effect of potassium excretion. Its acetate suspension is injected intramuscularly and intra-articularly, it decomposes and absorbs slowly, and it lasts for a long time. After intramuscular injection 6-8h, the average peak blood concentration is 14.8μg/L, which can be maintained for 11-17 days. . Its sodium succinate is water-soluble and can be injected intramuscularly or intravenously

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