Lubiprostone is a white crystalline powder, easily soluble in ether and ethanol, and almost insoluble in water.
Lubiprostone is a localized chloride channel activator, which can selectively activate type 2 chloride channels located on the luminal cell membrane at the tip of the gastrointestinal epithelium, increase the secretion of intestinal juice and the motility of the intestine, thereby increasing defecation, Alleviates symptoms of chronic idiopathic constipation without altering plasma sodium and potassium concentrations.
Lubiprostone is used to relieve stomach pain, bloating, and straining and produce softer and more frequent bowel movements in people who have chronic idiopathic constipation (difficult or infrequent passage of stools that lasts for 3 months or longer and is not caused by a disease or a medication).
