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Lokale anesthetica

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  • Specificaties:
  • product beschrijving
  • Productgebruik:
  • COA
productnaam Lidocaine Hydrochloride
Andere naam Lidocaine HCL
Testing Method USP
Assay ≥99.8%
Karakters Wit kristallijn poeder Cas No. 73-78-9
Moleculaire formule C 14 H 23 ClN 2 O Molecuulgewicht 270.7982
Applications 1. Local anesthetic.
2. Treating Epilepsy.
3. Treating Asthma.
Packing 1kg or 5kg/bag, 25kg/drum
Shelf Life 24 months
Opslag Store in sealed containers at cool & droge plaats. Protect from light, moisture and pest infestation.

lidocaïne, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine (aka adrenaline) vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e.g. for endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.

Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.

Test Items Specificatie Test Results
Karakters Wit kristallijn poeder Complies
Identificatie (1)Complies with the requirement
(2)Complies with the requirement
Complies
PH 4.5-5.5 4.64
Sulphated Ash ≤0.1% 0.05%
Water 5.0%-7.0% 6.43%
Heavy Metals ≤5ppm <5ppm
Residual solvents Methanol ≤0.5%
Toluene ≤0.089
0.068%
0.002%
Related Substances Impurities A≤0.01%
Total impurities ≤0.5%
Not detected
0.01%
0.13%
Assay 97.5%-101.0% 99.86%

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