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Farmaci anestetici locali

» Farmaceutici » Farmaci anestetici locali

  • specificazioni
  • Descrizione del prodotto
  • Utilizzo del prodotto
  • COA

nome del prodotto: Lidocaina
Another Name: Xylocaine
CAS:137-58-6
MF:C14H22N2O
MW:234.34
Saggio:99%
Aspetto esteriore: polvere bianca
Utilizzo:can be used to relieve pain

Lidocaina, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.

Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated.

Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine,though, has the advantage of a rapid onset of action.

Relative insensitivity to lidocaine is genetic.In hypokalemic sensory overstimulation, relative insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.

Lidocaina, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

Items Tested Specifica BP2007 Risultato
Personaggi White or slightly yellow crystal powder with characteristic odor White crystal powder with weak odor
Punto di fusione Punto di fusione: 66 degree to 70 grado 66.6 degree-68.5 degree
Identificazione BCDE
Comply with the requirement
Conforme
Appearance of solution Clear and colorless Conforme
Acqua Non più di 0.5% 0.3%
Sulphate Not more than0. 1% Conforme
Chloride Non più di 0. 0035% 0.0025%
Metalli pesanti Non più di 0.002% 0.001%
Residuo all'accensione Non più di 0.1% 0.02%
Impurità
(26-dimethylaniline content)
Non più di 0.01% Conforme
Saggio (HPLC) 99.0%-101.0% 99.50%

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