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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA
Product Name: Levamisole hydrochloride
CAS: 16595-80-5
MF: C11H13ClN2S
MW: 240.75
EINECS: 240-654-6

Levamisole Hydrochloride ( Levomisole HCL ), is an anthelmintic (anti-worm) agent commonly used in large livestock such as cattle, pigs and sheep. In 1971 it was found to have immunostimulatory properties and investigation into its use in humans began to expand.Currently, Levamisole Hydrochloride is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans.

Levamisole hydrochloride has good curative effect on roundworm, hookworm, pinworm and strongyloidiasis. Due to the high effective rate of this product in a single dose, it is suitable for group therapy. It is more active than diethylcarbamazine against filarial worms, Malayan filarial worms, and onchocerciasis adults and microfilariae, but the long-term efficacy is poor.

Items Standard Results
Characters A white or almost white crystalline powder. A white crystalline powder.
Identification Specific optical rotation Qualified
IR
Gives reaction of chlorides
Related substances Each of impurities
A, B, C, D, E≤0.2%
A: 0.02%, B: 0.01%,
C: 0.09%, D: 0.00%,
E: 0.00%
Any other impurity≤0.1% 0.01%
Total impurities≤0.3% 0.10%
Loss on drying ≤0.5% 0.1%
Sulfated ash ≤0.1% 0.03%
Heavy metals ≤0.002% <0.002%
Assay 98.5%~101.0% 100.1%
Storage Should be protected from light protected from light
CONCLUSION The product complies to the standard of BP2011, EP7.0

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