namn:Icatibant Acetat
Cas nr:138614-30-9
Formel: C59H89N19O13S.C2H4O2
Molekyl:1364.57
Sekvens:D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-Tic-Oic-Arg-OH
Renhet:98%
Utseende: vitt pulver
Källa: syntetisk
Också känd som: Firazyr, Icatibant , HOE140, AC1Q5QRX, HUR 140, VINNA 65365
Icatibant is a peptidomimetic drug consisting of ten amino acids, which is a selective and specific antagonist of bradykinin B2 receptors. It has been approved by the European Commission for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency.
A ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Att vara, D-Tic, Oic, and Arg residues joined in sequrence.A bradykinin receptor antagonist used as its acetate salt for the treatment of acut attacks of hereditary angioedema in adult patients.
