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Peptides pharmaceutiques

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  • Caractéristiques
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Nom:Gonadorelin
Synonymes anglais: Gonadorelin acetate
Numero CAS: 33515-09-2
Formule moléculaire: C55H75N17O13
Masse moléculaire: 1182.31
Numéro EINECS: 251-553-1

Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland. GnRH causes the pituitary gland to release other hormones (hormone lutéinisante [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults.

Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough GnRH.

Gonadorelin is a hormone that is produced naturally by the hypothalamus in the brain. It is also known as gonadotrophin-releasing hormone or GnRH.

Gonadorelin stimulates the pituitary gland in the brain to release the sex hormones luteinising hormone (LH) and follicle stimulating hormone (FSH). In women, FSH stimulates the production of oestrogen and the development of eggs in the ovaries. LH stimulates the ovaries to release an egg (ovulation). In men, LH stimulates the testicles to produce the hormone TEST and FSH stimulates the testicles to produce sperm.

Gonadorelin is given by injection to check whether the pituitary gland is producing LH and FSH in the correct levels. This can help in the diagnosis of various hormonal disorders, including infertility, delayed puberty and hypogonadism.

The gonadorelin is given as a single injection either under the skin or into a vein.Blood samples to measure the levels of LH and FSH in the blood are usually taken 15 minutes before the gonadorelin injection, immediately before the injection and then at 15, 30, 45, 60 et 120 minutes after the injection.

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