Folistatin 344 CAS:80449-31-6

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.

Folistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.

In short, follistatin does build muscle but not necessarily in humans.A number of studies support the muscle-building and anti-degenerative effects follistatin in rodents.Unfortunately there is no formal research examining follistatin usage in human subjects but a quick Google search will yield countless amateur follistatin logs on bodybuilding and fitness forums.

When scientists bred a mouse producing no myostatin and extra follistatin it had 117% larger muscle fibers and 73% more total muscle fibers compared to the mice in the control group.[8] This study demonstrates that follistatin positively impacts muscle growth in ways beyond simply suppressing myostatin.Mice with suppressed myostatin had twice the muscle mass but mice with the follistatin transgene and suppressed myostatin had four times as much muscle mass compared to the control group.

Administering FS344 via a small virus (re:Adeno-associated virus/AAV) can increase muscle size and strength in animal species ranging from mice to monkeys with no significant adverse effects on organs, reproductive capabilities, serum estradiol (re:Primary female sex hormone), luteinizing hormone (LH), and FSH levels.When scientists administered follistatin in mice with spinal muscular atrophy, the mice experienced increased muscle mass, improved motor function, and a 30% longer lifespan compared to mice in the control group.

Not only do increased follistatin levels correlate to increased muscle mass, but a lack of the follistatin protein at birth directly correlates to less muscle mass.Less muscle mass at birth can negatively impact bone, organ, and tissue development as well as normal hormonal function.

Total vials on one course - 2 Folistatin 344 vial to 1 mg of active ingredient each. Makes 1 injection per day in the morning for 100 mcg subcutaneously in the abdominal oblique muscles. Peptide may be used locally. There are versions that in this case the drug increases the target muscle to a greater extent than others. After 10 days of use is the same 10-day break. After this break, it is recommended to start a new 10-day cycle.