nome del prodotto:Flutammide
CAS:13311-84-7
MF:C11H11F3N2O3
MW:276.21
EINECS:236-341-9
MP:112 °C
Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR).
Flutamide belongs to a class of drugs known as anti-androgens . Testosterone is a natural hormone, helps prostate cancer to grow and spread. Flutamide works by blocking the effects of testosteron, thereby slowing the growth and spread of prostate cancer.
| Elementi |
Standard |
| Caratteristiche |
Pale yellow crystalline powder |
| Identificazione |
UN:IR Absorption
B:HPLC |
| Intervallo di fusione |
110-114C( does not exceed 2ºC) |
| Perdita all'essiccamento |
Non più di 0.5% |
| Residuo alla combustione |
Non più di 0.1% |
| Related compounds |
4-Nitro-3-trifluoro-methylacetanilide:
NMT: 0.2% |
4-Nitro-3-trifluoro-methylaniline:
NMT: 0.15% |
|
NMT: 0.2% |
| 4-Nitro-3-trifluoromethylpropionanilide: NMT: 0.3% |
3-trifluoromethylisobutyranilide:
NMT: 0.2% |
| o-Flutamide:NMT: 0.2% |
Unknown(relative response:1.0) :
NMT: 0.05% |
| Total unknown:NMT: 0.1% |
| Total impurities:NMT: 0.4% |
| Residual solvents |
Meth anol:NMT:3000ppm |
| Solubilità |
Freely soluble in acetonemia
soluble in chloroformate other practically
insoluble mineral oil.
and water |
| Metalli pesanti |
Not more than10ppm |
| Saggio |
98.0-101.0%
(calculated on the dried basis) |
