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Pharmaceutical Peptides

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Nomen chemicum

Anguilla calcitonin

Synonyma

Calcitonin (anguillae);HC 58;Anguilla Thyrocalcitonin;

CAS No.

57014-02-5

Formulae hypotheticae

C146H241N43O47S2

M. Pondus

3414.87000

PSA

1512.56000

LogP

-1.69450

Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Autem, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.

Calcitonin can be used as a drug to treat calcium and phosphorus metabolic disorders, and can be used to treat hypercalcemia, osteitis deformation, osteoporosis, hyperphosphatemia, ulcer disease, as well as the diagnosis of thyroid myelocellular carcinoma and lung cancer. Neurodystrophy and calcium, phosphorus metabolic disorders such as hypercalcemia, hyperphosphatemia, ulcer disease, acute pancreatitis. It is also used to diagnose thyroid and medullary cell carcinoma and lung cancer.

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