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Active Pharmaceuticals

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Product Name Diatrizoate Sodium
Synonym 3,5-DIACETAMIDO-2,4,6-TRIIODOBENZOIC ACID SODIUM SALT;3,5-BIS[ACETYLAMINO]-2,4,6-TRIIODOBENZOIC ACID, SODIUM;DIATRIZOIC ACID SODIUM SALT;Diatrizoate Sodium;Hypaque Sodium; LABOTEST-BB LT00455174;SODIUM DIATRIZOATE; Sodium amidotrizoate
CAS NO 737-31-5
MF C11H8I3N2NaO4
MW 635.9
EINECS 212-004-1
Melting Point 261-262°(dec)
Purity 99%
Appearance White Powder
Solubility H2O: 0.35 g/mL, slightly turbid, colorless
Usage Water-soluble contrast agent, commonly used in urography, but also for kidney, cardiovascular, cerebral angiography

Diatrizoic acid (or its anionic form, diatrizoate), also known as amidotrizoic acid, or 3,5-diacetamido-2,4,6-triiodobenzoic acid, is a radiocontrast agent containing iodine.

Diatrizoate sodium is a contrast agent used during the X-rays test. It can be used as a diagnostic aid agent during angiography, urography and radiography. It can be applied during visualizing veins, the urinary system, gastrointestinal tract, spleen and joints as well as during the computer tomography (CT scan). It is used in cases where barium is not suitable for application such as patient being allergic to barium. The mechanism of action of Diatrizoate sodium is that it can block the X-rays so that the body structure containing iodine to be delineated in contrast to those structures that free of iodine, further allowing the visualization of those related areas.

Diatrizoate sodium is used in cases where barium is not suitable for application such as patient being allergic to barium. The mechanism of action of Diatrizoate sodium is that it can block the X-rays so that the body structure containing iodine to be delineated in contrast to those structures that free of iodine, further allowing the visualization of those related areas.

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