Buserelinacetat CAS:68630-75-1

Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis.It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy.In addition, buserelin is used in veterinary medicine.The medication is typically used as a nasal spray three times per day, but is also available for use as a solution or implant for injection into fat.

Side effects of buserelin are related to sex hormone deprivation and include symptoms of low testosterone levels and low estrogen levels such as hot flashes, sexual dysfunction, vaginal atrophy, and osteoporosis.Buserelin is a gonadotropin-releasing hormone agonist (GnRH agonist) and works by preventing the production of sex hormones by the gonads.It can lower sex hormone levels by about 95% in both sexes.Buserelin is a peptide and an analogue of GnRH.

Etilamide; HOE-766; HOE-766A; ICI-123215; S-746766; D-Ser(tBu)⁶EA¹⁰-LHRH; 6-[Ö-(1,1-Dimethylethyl)-D-serine]-9-(N-Äthyl-L-prolinamide)-10-deglycinamide-LHRH (pig)