Product Name : Betamethasone 17-valerate
CAS No : 2152-44-5
Molecular formula : C27H37FO6
Molecular weight : 476.58
Content : 99%
Betamethasone-17-valerate is a high-potency topical fluorinated corticosteroid with low systemic effects. It has been classified as group D by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.
Betamethasone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. Betamethasone foam is used for scalp problems. This medicine is a corticosteroid (cortisone-like medicine or steroid).
1)Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate
2)been shown to inhibit heat-induced vasodilatation in man.
3)Antiepileptic non-selective phosphodiesterase inhibitor
4)Betamethasone 17-valerate is a glucocorticoid with anti-inflammatory and immunosuppressive activity.
5)A potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
| Test Items |
Betamethasone Valerate |
Results of Analysis |
| Appearance |
White or almost white crystalline powder |
Complies |
| Solubility |
soluble in acetone and in methylene |
Complies |
| Identification |
Complies with the Standard |
Complies |
| Specific rotation |
+75°～+82° |
+76.5° |
| Loss on drying |
≤0.5% |
0.09% |
| Residue on ignition |
≤0.2% |
0.05% |
| any individual impurity |
≤1.0% |
0.79% |
| total impurities |
97.0%～103.0% |
100.20% |
| Particle size |
100% ≤30Microns |
Complies |
| Residual solvents |
Meet the ICH requirements |
complies |
| Conclusion |
The specification comply with USP35 Standard |
