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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA

Product Name : Betamethasone 17-valerate

CAS No : 2152-44-5

Molecular formula : C27H37FO6

Molecular weight : 476.58

Content : 99%

Betamethasone-17-valerate is a high-potency topical fluorinated corticosteroid with low systemic effects. It has been classified as group D by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.

Betamethasone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. Betamethasone foam is used for scalp problems. This medicine is a corticosteroid (cortisone-like medicine or steroid).

1)Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate

2)been shown to inhibit heat-induced vasodilatation in man.

3)Antiepileptic non-selective phosphodiesterase inhibitor

4)Betamethasone 17-valerate is a glucocorticoid with anti-inflammatory and immunosuppressive activity.

5)A potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

Test Items Betamethasone Valerate Results of Analysis
Appearance White or almost white crystalline powder Complies
Solubility soluble in acetone and in methylene Complies
Identification Complies with the Standard Complies
Specific rotation +75°~+82° +76.5°
Loss on drying ≤0.5% 0.09%
Residue on ignition ≤0.2% 0.05%
any individual impurity ≤1.0% 0.79%
total impurities 97.0%~103.0% 100.20%
Particle size 100% ≤30Microns Complies
Residual solvents Meet the ICH requirements complies
Conclusion The specification comply with USP35 Standard

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