Beclomethasone Dipropionate CAS:5534-09-8

Beclomethasone dipropionate is a prodrug of the free form, Beclomethasone (beclomethasone-17-monopropionate). An anti-inflammatory, synthetic corticosteroid, it is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma and allergic rhinitis (seasonal and perennial). Beclometasone dipropionate is also being investigated for oral treatment in mild-to-moderate Crohn's disease of ileal or ileal-right colonic localisation and for "topical" use mild-to-moderate graft versus host disease. It is marketed under several brand names such as Qnasl (US) and Rivanase AQ (Kanada).

Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication.It is available as an inhaler, cream, pills, and nasal spray.The inhaled form is used in the long-term management of asthma.The cream may be used for dermatitis and psoriasis.The pills have been used to treat ulcerative colitis.The nasal spray is used to treat allergic rhinitis and nasal polyps.

Common side effects with the inhaled form include respiratory infections, headaches, and throat inflammation. Serious side effects include an increased risk of infection, cataracts, Cushing’s syndrome, and severe allergic reactions.Long-term use of the pill form may cause adrenal insufficiency.The pills may also cause mood or personality changes.The inhaled form is generally regarded as safe in pregnancy.Beclometasone is mainly a glucocorticoid.