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Farmaceutické peptidy

» Peptidy » Farmaceutické peptidy

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Meno Produktu Alarelin Acetate
Sekvencia Glp-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
Cas č. 79561-22-1
Molekulárny vzorec C56H78N16O12
Molekulová hmotnosť 1167.3
Čistota (HPLC) 98%min.
Vzhľad Biely prášok
Jediná nečistota(HPLC) 1.0%max
Aminokyselinové zloženie ±10 % teoretickej hodnoty
Obsah peptidov(N %) ≥80,0 %
Obsah vody(Karl Fischer) ≤ 8,0 %
Obsah acetátu(HPIC) ≤ 12,0 %
Špecifická rotácia (20/D) -37.0~-47.0°(c=1 1%HAc)
PANI(ESI) Konzistentné
Hmotnostná bilancia 95.0~105,0 %

1. Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland.

2. Alarelin acetate is a gondatrophin releasing hormone. Natural forms of alarelin found in animals are used to induce ovulation. Synthetic versions of this product are created using an LH-RH antagonist which is commonly set in larger doses than the natural LH-RH that is typically found in the rat hypophyseal stimulation or the gondatoropin secretions in induced ovulation or in vitro.

3.This chemical is the acetate form of the natural hypothalamic peptide which is used by an animal's body to release LH and FSH from the pituitary gland. The peptide alarelin acetate has a single non-glycosylated polypeptide structure that is made up of nine amino acids.

1. Alarelin is commonly used in research settings both to better understand this peptide's effects on an animal's body and to induce conditions that may assist with reproductive research. Samples of this chemical intended for research settings are typically stable for around three weeks at room temperature, and will need to be stored at temperatures below -18 degrees Celsius for long term use.

2. Alarelin (Gonadotrophin-releasing hormone) is a synthetic LH-RH agonist that is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation. Alarelin acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland

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