Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate.
It is an ester derivative of 17α-hydroxyprogesterone formed from c aproic acid (hexanoic acid). Mimicking the action of progesterone, hydroxyprogesterone caporate binds to and activates nuclear progesterone receptors in the reproductive system and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes.
Due to the negative feedback mechanism seen with progesterone, this agent also blocks luteinizin g hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium.
Par ailleurs, without stimulation of LH, estrogen release from the ovaries is stopped, hence impeding the growth of estrogen-sensitive tumor cells.
Hydroxyprogesterone caproate (OHPC) is a progestin medication which is used to prevent preterm birth in pregnant women with a history of the condition and to treat gynecological disorders. It is also used in combination with an estrogen as a form of long-lasting injectable birth control.
Hydroxyprogesterone Caproate is a synthetic progestational agent. It binds and activates nuclear progesterone receptors in the reproductive system, inhibiting ovulation, cervical mucus and changes in the endometrium.
Hydroxyprogesterone Caproate is a synthetic progestin that reduces the chances of pre-term birth in women and improves specific fetal outcomes..
