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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA
Product Name: Xylazine
CAS No: 7361-61-7
Molecular formula: C12H16N2S
EINECS No. 230-902-1
Melting point: 140°C
Boiling point: 334.2±52.0 °C(Predicted)
Type: Pharmaceutical intermediates
Appearance: Powder
Color: White
Purity: 99.9%
pka: 7.67±0.20(Predicted)
Storage: -20°C

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.

Xylazine is recognized as a short-acting tranquilizer or sedative that provides significant pain relief. Acting as a muscle relaxant through its effects on the central nervous system, it is commonly used for short-term sedation, and treatment and management of colic.

Xylazine can be administered intravenously, intramuscularly, subcutaneously or orally. The commercial product contains 23.32 mg/ml xylazine hydrochloride in water based injectable solution. Xylazine can be obtained also as pure crystalline powder. There is a significant species dependent response to xylazine administration. Intramuscular dose of up to 0.3 mg/kg for cattle has been suggested by the manufacturer. The recommended doses for horses were 0.6 mg/kg and for sheep 1.0 mg/kg. For dogs the dose was even higher.Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.

ITEMS OF TEST
STANDARD
RESULTS OF ANALYSIS
Appearance
White to almost white crystalline powder
White crystalline powder
Identification
A: Infrared absorption
B: Ultraviolet absorption
C: Thin-layer chromatographic identification
Conforms
Conforms
Conforms
Loss of drying
NMT 0.50%
0.31%
Melting range
136 -142
Confirms
Heavy metals
NMT 20ppm
<20ppm
Residue on ignition
NMT 0.10%
0.05%
3-Amino-1-propanol
NMT 0.50%
0.18%
Acetone
NMT 0.020%
Negative
Isopropyl alcohol
NMT 0.20%
Negative
Chromatographic purity
Total impurities: NMT1.00%Single impurity: NMT0.50%
Conforms
Conforms
Assay
Not less than 98.00% and not more than 102.00%
99.64%

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