China Anabolic Steroids Powder Manufacturer
EnglishAfrikaansБългарскиNederlandsFrançaisDeutschItaliano日本語LatīnaNorskپارسیPolskiPortuguêsRomânăРусскийSlovenčinaSlovenščinaEspañolSvenskaTürkçeУкраїнськаудмурт кыл

Local Anesthetic Drugs

» Pharmaceuticals » Local Anesthetic Drugs

  • Specifications
  • Product Description
  • Product Usage
  • COA

Product Name: Tetracaine hydrochloride
Synonyms: Tetracaine HCL
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
mp: 149°C
storage temp: Refrigerator
Appearance: White Solid
Usage: Local anesthetic; Mainly used in mucosa anesthetic.The function is stronger than Procaine and Lidocaine.

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine HCL is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction.

Tetracaine Hcl is a potent local anesthetic of the ester group.It is mainly used topically in ophthalmology and as an antipruritic,and it has been used in spinal anesthesia.

Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours.

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine,though, has the advantage of a rapid onset of action.

In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.

Items QUALITY STANDARDS RESULTS
Description White or almost white crystalline powder White crystalline
powder
Solubility Matching with the working standard Complies
A.By IR, To match with working standard Complies
Identification B: To 10ml of solution S add 1ml of ammonium thiocyanate solution
R.A white,crystalline precipitate is formed which,after recrystallisation
from water R and drying at 80ºC for 2h,melts at about 131ºC
Complies
C. To about 5mg add 0.5ml of fuming nitric acid R .Evaporate to
dryness on a waterbath,allow to cool and dissolve the residue in
5ml of acetone R.Add 1ml of 0.1M alcoholic potassium hydroxide.
A violet colour develops
Complies
D. Solution S gives reaction of chlorides. Complies
PH 4.5~6.5 5.78
Residual Solvents Conform to standard Complies
Claruty Solution should be clear Complies
Related Substances Conform to standard Complies
Heavy metals ≤10ppm <10ppm
Loss on drying ≤1.0% 0.87%
Resiue on ignition ≤0.1% 0.05%
Melting range 148ºC 147.5ºC~150.8ºC
Assay(*) 99%~101.0% 100.40%

 

Enquiry Form ( we will get back you as soon as possible )

Name:
*
Email:
*
Message:

Verification:
5 + 5 = ?

Maybe you like also

  • Our Advantage

    Good Price

    High Quality

    Fast Delivery

    Safe Shipment

    Excellent After-sale Service

  • Local Warehouse

    EU Warehouse

    UK Warehouse

    USA Warehouse

    Canada Warehouse

    Australia Warehouse

  • Payment Method

    Paypal

    Bitcoin

    Bank Wire

    Money Gram

    Western Union

  • Contact Us

    Email: jacob@steroid-peptide.com

    WhatsApp: +8615636286252

    Phone: 0086-15636286252

    Website: www.steroid-peptide.com

    Welcome your inquiry