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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA
Product Name: Scopolamine hydrobromide
CAS: 114-49-8
MF: C17H22BrNO4
MW: 384.26
EINECS: 204-050-6
Product Categories: API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Alkaloids;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;
Mol File: 114-49-8.mol

Scopolamin hydrobromide is the hydrobromide salt of the anticholinergic natural product Scopolamin, isolated from plants of the Solanaceae family. Scopolamin exhibits anticholinergic properties through competitive inhibition of acetylcholine muscarinic receptors with selectivity for mAChR M1. Suppression of the cholinergic response results in decreased activity of the parasympathetic nervous system, widely exploited in studies concerning parasympathetic functioning.

Scopolamine Hydrobromide is pharmceutical material for peripheral anticholinergic drugs which can smooth muscle spasm, ease the gastrointestinal tract, bile duct and urinary tract and inhibit peristalsis. It applies to the stomach, duodenum, colon fiber endoscopic examination as the operative peparation, so it can be used for the treatment of gastrointestinal spasm, biliary Colic, renal colic or gastrointestinal peristalsis, such as hyperthyroidism.

1. This product is a peripheral role stronger anticholinergic activity, blocking M choline receptor.

2. This product is peripheral role of atropine strong and maintain time is short, the respiratory center a cordial, central role to suppress give priority to.

3. Can restrain glands secretion, remove capillary vessel spasm, improve microcirculation, dilated bronchi, remove smooth muscle convulsion.

4. On the brain sedative and hypnotic effects, the respiratory center a cordial.

Analysis
Specification
Results
Assay
≥99%
99.5%
Appearance
White crystalline powder
Complies
Melting point
59 ºC
Complies
Specific rotation
-24°~ -27°
-25.8°
Ash
≤8.0%
3.0%
Moisture
≤13.0%
9.5%
Pesticides
Negative
Complies
Heavy metals
≤10ppm
Complies
Odor
Characteristic
Complies
Particle size
100% through 30 mesh
Complies
Microbioiogical:
Total of bacteria
≤1000cfu/g
Complies
Fungi
≤100cfu/g
Complies
Salmgosella
Negative
Complies
Coli
Negative
Complies

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