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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA
Product Name Praziquantel/Biltricide
CAS 55268-74-1
MF C19H24N2O2
EINECS 217-244-0
Melting Point 259-559-6
Storage conditions Sealed in dry,Store in freezer, under -20°C

Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Praziquantel is on the World Health Organization's List of Essential Medicines,a list of the most important medications needed in a basic health system. Praziquantel is not licensed for use in humans in the UK;it is,however,available as a veterinary anthelmintic,and is available for use in humans on a named-patient basis.

(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of praziquantel.
(2) Praziquantel is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.
(3) Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.

TESTS SPECIFICATIONS&LIMITS RESULTS
Characters White or white crystalline powder Complies
Solubility slightly soluble in water, freely soluble in Complies
alcohol and in chl oroform
Identification IR: Corresponding to Praziquantel CRS Positive
Melting Range 136°C~142°C 137.8~139.5°C
Heavy metals Not more than 0.002% <0.002%
Phosphate Not more than 0.05% <0.05%
Loss on drying Not more than 0.5% 0.24%
Residue on ignition Not more than 0.1% 0.03%
Related compound A: not more than 0.2% A: 0.09%
Related Substances Related compound B: not more than 0.2% B: 0.11%
Related compound C: not more than 0.2% C:Not detectable
Assay 98.5%~101.0% (dried basis) 99.38%
Particle size 20% less than 10um
97% less than 50um
Residual Solvents Limit of chloroform: NMT 60 ppm NMT 60 ppm
Limit of acetone: NMT 500 ppm NMT 500 ppm
Conclusion Conform with USP32

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