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Nootropics

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  • COA

Product: Phenibut HCL
Other Name: 3-Amino-4-phenylbutyric acid hydrochloride
CAS: 3060-41-1
MF: C10H14ClNO2
MW: 215.68
MP: 194-201°C
Storage Temp.: Store at RT
Appearance: White Solid
Usage: Nootropics

Phenibut is a central depressant and analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), or a GABA analogue. The addition of a phenyl ring allows phenibut to cross the blood-brain barrier. Phenibut was developed in the Soviet Union in the 1960s, and has since been used there as a pharmaceutical drug to treat a wide range of ailments, including posttraumatic stress disorder, anxiety, depression, asthenia, insomnia, alcoholism, stuttering, and vestibular disorders, and other conditions.

Phenibut is a close structural analogue of GABA, as well as of baclofen (β-(4-chlorophenyl)-GABA), pregabalin (β-isobutyl-GABA), and GABOB (β-hydroxy-GABA). Phenibut is believed to act as a selective GABAB receptor agonist; studies are conflicting as to whether phenibut also acts as a GABAA receptor agonist. More recently, phenibut has been found to act preferentially as a blocker of α2δ subunit-containing voltage-gated calcium channels, similarly to gabapentin and pregabalin. As such, by definition, phenibut is a gabapentinoid.

The recommended serving size of Phenibut is 500 - 2000mg per day, in up to two to three separate servings, depending on the desired effect.Phenibut should not be consumed in amounts exceeding 4 grams total per week, and should NEVER be taken in higher amounts on consecutive days due to rapid development of tolerance to the benefits.

Items of analysis Specification Results
Appearance White crystalline powder White crystalline powder
Identification Chemical or IR Method Positive
pH 2.3~2.7 2.60
Loss on Drying ≤0.5% 0.19%
Assay ≥99.0% 99.34%
Melting Point 194 ºC ~202 ºC 198.0 ºC ~199.5 ºC
Residue on Ignition ≤0.1% 0.04%
Related substance ≤0.5% 0.01%
Heavy Metals ≤10ppm <10ppm
Iron ≤50ppm <50ppm
Sulfate ≤500ppm <500ppm
Arsenic ≤2ppm <2ppm
Lead ≤3ppm <3ppm
Mercury ≤0.1ppm <0.1ppm
Cadmium ≤1ppm <1ppm
Conclusion Qualified

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