Oligopeptide-10 has broad-spectrum activity against many types of organisms, including p. acne bacteria. Oligopeptide-10 is A short bioactive peptide consisting of fifteen naturally occurring amino acids that provides anti-microbial activity against p-acne bacterium.
Oligopeptide-10 has potent activity against Propionibacterium acnes causing rapid cell death. It binds to negatively charged surface elements (lipoteichoic acids) of bacteria enabling access to its primary target, the cytoplasmic membrane which causes a lethal osmotic imbalance within the bacteria. Due to this unique mechanical mechanism of action bacteria have a very low probability of becoming resistant and bacteria resistant to other antibiotics remain susceptible to Oligopeptide-10. In addition, it neutralizes pro-inflammatory bacterial components, reducing redness. In independent studies Oligopeptide-10 has been shown to be non-cytotoxic, non-mutagenic, non-irritating and non-sensitizing.
1. Oligopeptide-10 Can be formulated into oil-in-water emulsions, water-in-oil emulsions and other formula types;
2. Oligopeptide-10 is ready to dilute into an active containing water phase or improving an existing o/w emulsion;
3.Add to the water phase of all emulsion types.
