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Active Pharmaceuticals

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  • COA

Name:Moxifloxacin HCl
CAS No.:186826-86-8
Other Names: Moxifloxacin hydrochloride
MF: C21H25ClFN3O4
EINECS No.:641-756-7
Type: Antibiotic and Antimicrobial Agents
Grade Standard: Medicine Grade
Purity:99%
Appearance: White Crystalline Powder
Molecular Weight:437.892
Storage:2-8°C

Moxifloxacin hydrochloride is a broad spectrum and antimicrobial activity of 8- methoxy quinolone antibacterial drug with.In vitro showed against gram positive bacteria, gram negative bacteria, anaerobic bacteria, acid fast bacteria and atypical organisms such as Mycoplasma, chlamydia and Legionella have broad-spectrum antibacterial activity.

Moxifloxacin hydrochloride antibacterial mechanism for the interference of II, IV topoisomerase. Topoisomerase is to control the DNA topology and in DNA replication, repair and transcription of key enzyme.

Moxifloxacin hydrochloride bactericidal curves show, moxifloxacin hydrochloride is a concentration dependent bactericidal activity. Minimum bactericidal concentration and minimum inhibitory concentration is consistent. Moxifloxacin hydrochloride on b- lactam and a macrolide antibiotic resistant bacteria are effective.

Moxifloxacin hydrochloride is used to treat patients suffering from upper respiratory tract infections and lower respiratory tract of adults (≥ 18 years),such as:acute sinusitis,acute exacerbation of chronic bronchitis,community-acquired pneumonia, and skin and soft tissue infections.

Item Specification Result
Assay 99% 99.68%
Appearance White powder conforms
Odor Characteristic conforms
Taste Characteristic conforms
Particle Size NLT 100% Through 80 mesh conforms
Loss on Drying <2.0% 0.46%
Heavy metals
Total Heavy Metals ≤10ppm conforms
Arsenic ≤3ppm conforms
Lead ≤3ppm conforms
Microbiological Tests
Total Plate Count ≤1000cfu/g conforms
Total Yeast & Mold ≤100cfu/g conforms
E.Coli Negative Negative
Salmonella Negative Negative

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