INCI Name: Melanostatin DM
Cas No: 123689-72-5
Formula: C41H58N14O6
Molecular: 842
Sequence : His-D-Arg-Ala-Trp-D-Phe-Lys-NH2
Purity: >98%
Grade: cosmetic
Source: synthetic
Solubility: soluble in water
Stability: stable
Appearance: white powder
Melanostatin DM is an inhibitor of α-melanocyte stimulating hormone (alpha;-MSH), which is the primary hormone that controls production of melanin pigment. By inhibiting the effects of α-MSH, Melanostatin DM is able to lighten skin tone and even out skin coloration in laboratory experiments. It may be useful for the treatment of photodamage (skin discoloration due to sun exposure) as well as other conditions in which melanin production needs to be reduced.
Melanostatin DM is being actively invested in animal and in vitro models for its ability to interfere with melanin production. The molecule is thought to interfere with tyrosinase activity by inhibiting the actions of α-MSH. It may be useful in the treatment of disease that cause skin discoloration, such as disease and diabetes.