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Female Steroids

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Product Name:Medroxyprogesterone Acetate
CAS:71-58-9
MF:C24H34O4
MW:386.52
EINCES:200-757-9
Appearance:white powder

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.Target: Progesterone ReceptorMedroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications.

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.Target: Progesterone ReceptorMedroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications.

Though not used as a treatment for epilepsy, MPA reduces the frequency of seizures and does not interact with antiepileptic medications. MPA does not interfere with blood clotting and appears to improve blood parameters for
women with sickle cell anemia. Similarly, MPA does not appear to affect liver metabolism, and may improve primary biliary cirrhosisand chronic active hepatitis.
Women taking MPA may experience spotting shortly after starting the medication but is not usually serious enough to require medical intervention. With longer use amenorrhoea can occur as can irregular menstruation which is a major source of dissatisfaction, though both can result in improvements with iron deficiency and risk of pelvic inflammatory disease and often do not result in discontinuing the medication.

ITEMS SPECIFICATION RESULTS
Character White or almost white crystalline powder Almost White crystalline powder
Specific optical rotation +47°to +53° +48.2°
Impurity F Not more than 0.5% <0.5%
Identification Complies by IR Conforms
Related substances Impurity A not more than 0.3% Undetected
Impurity B not more than 0.7% Undetected
Impurity C not more than 0.2% Undetected
Impurity D not more than 1.0% 0.36%
Impurity E not more than 0.2% Undetected
Impurity G not more than 0.2% Undetected
Impurity H not more than0.10% 0.08%
Impurity I not more than 0.2% Undetected
Unknown impurity not more than 0.10% 0.05%
Total impurity not more than 1.5% 0.49%
Loss on drying Not more than 1.0% 0.20%
Assay Contains 97.0% to 103.0% of C24H34O4 99.80%
Calculated on dried basis
Conclusion The goods conforms to USP

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