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Amino Acid Supplements

» Pharmaceuticals » Amino Acid Supplements

  • Specifications
  • Product Description
  • Product Usage
  • COA
Name L-Glutamic acid
CAS 56-86-0
EINECS 200-293-7
MF C5H9NO4
MW 147.13
MP 205 °C (dec.)(lit.)
Storage temp Store at RT.
Assay 98% Min.
Appearance White Crystalline Solid
Usage A non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecu le in cellular metabolism.

Glutamic acid (symbol Glu or E;the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is non-essential in humans, meaning the body can synthesize it. It is also an excitatory neurotransmitter, in fact the most abundant one, in the vertebrate nervous system. It serves as the precursor for the synthesis of the inhibitory gamma-aminobutyric acid (GABA) in GABA-ergic neurons.

1. It can be used for the pharmaceutical, food additives, and nutritional supplements.
2. It can be used for biochemical research. In medicine, it can be used for treating hepatic coma, seizures prevention, and reducing ketonuria and ketosis.
3. It can be used as salt substitute, nutritional supplements, and flavor enhancer (mainly for meat, poultry, soups and so on). It can also be used as the prevention agent for the production of magnesium ammonium phosphate in shrimp, crabs and other aquatic can with the usage amount of 0.3% to 1.6%. According to the provisions of GB 2760-96, it can be used as a spice.
4. L-glutamate is mainly used for the production of monosodium glutamate, spices, and as a salt substitute, nutritional supplements and biochemical reagents. L-glutamate itself can be used as drugs and is involved in protein and carbohydrate metabolism in the brain, promoting the oxidation process. This product can combine with ammonia in the body into non-toxic glutamine, causing decreasing ammonia and reducing the symptoms of hepatic coma. It is mainly used for the treatment of hepatic coma and severe hepatic dysfunction. However, the efficacy is not satisfied; Combination with antiepileptic drugs can treat seizures and psychomotor seizures. Racemic glutamate can be used in the production of drugs as well as being used as biochemical reagents.

Items Standards Results
Appearance White or off-white solid powder Complies
Identification By IR Complies
By HPLC Complies
Solubility Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water Complies
Polymorphic Form Polymorphic form 1 Complies
Melting Point 211ºC~216ºC 212.8ºC~214.9ºC
Water Content ≤ 0.50% 0.10%
Heavy Metals ≤ 20ppm Complies
Residue on Ignition ≤ 0.20% 0.09%
Related Substance Any single impurity: ≤0.10% 0.06%
Total Impurities: ≤1.00% 0.16%
Assay                  (on the anhydrous basis) 98.0%~102.0% 99.94%
Particle Size D90: ≤100µm Complies
Reference Standard In-house Standard
Conclusion The product complied to In-house standard.

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