Synonyms |
Somatotropin (176-191) |
CAS |
66004-57-7 |
Purity |
98% min |
Molecular formula |
C78H123N23O22S2 |
MW |
1799.1 |
Appearance |
White Powder |
Grade |
Pharmaceutical Grade |
Storage |
Closed, below 2 ~ 8ºC preservation |
HGH Fragment (176-191) is a fat-loss peptide derived from the GH molecule, which directly initiates lipolysis and inhibits lipogenesis, but in order to better understand this peptide, it is imperative to have at least a rudimentary understanding of its parent hormone .
GH is a polypeptide which contains an amino acid sequence that is 191 amino acids in length. Frag (176-191) was developed by isolating and modifying the specific portion of the GH molecule responsible for the hormone's lipolytic and anti-lipogenic effects.
The portion of the molecule responsible for these effects is amino acids 176-191. In every sense, Frag should primarily be considered a fat loss peptide which performs these functions through the same pathways as traditional GH, but without exposing the user to the potentially undesirable side effects which may present themselves during GH administration.
HGH fragment 176-191 is an analog of the growth hormone-releasing factor (GRF) which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of HGH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.
These segments of the synthetic peptide hgH 176-191 have been investigated for their in vivo effects in laboratory mice musculus. Research results have shown that hgH 176-191 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978).
In order to reap the benefits of HGH Frag, users will need to dose around 500mcgs per day. This can be done by dosing 250mcgs in the morning pre-workout, and 250mcgs before lunch or 250mcgs before bed. Users will also want to take note of the timing of injections and their diet at that time. It is optimal to inject HGH Frag 176-191 on an empty stomach or with just protein in the stomach. Like other peptides, HGH Frag has been noted to not work as effectively in the presence of carbohydrates and sugars.