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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA

Product name: Guaifenesin
Other name: Guaiphenesin
Appearance: White Powder
CAS NO.: 93-14-1
M.F.: C10H14O4
M.W.: 198.216
Grade: Pharmaceutical grade

Guaifenesin is an expectorant reported to have muscle relaxant and sedative activity, where it is often used as anesthetic during animal surgery.

The principal use of guaifenesin powder is in the treatment of coughing, but the drug has numerous other uses,including medical, veterinary, and personal.Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It also stimulates the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx.Thus, it may increase the efficiency of the cough reflex and facilitate removal of the secretions.

Items Specification
Appearance White crystalline powder
Identification

Infrared Absorption

Ultraviolet Absorption

Chemical test

Concordant with the RS spectrumConcordant with the RS spectrum

Positive

Melting range 78 ~ 82℃
Loss on drying ≤ 0.5%
Heavy Metal ≤ 0.0025%
Chromatographic Purity

Β-isomer

Guaiacol

Other individual impurity

Bisether

1,3-bis(2-methoxyphenoxy) propan-2-ol

Other individual maximum unknown impurity

Total impurities

Residual solvent ( Ethanol)

≤ 1.5%≤ 0.03%

≤ 0.5%

≤ 0.5%

≤ 0.10%

≤ 1.0%

≤ 0.5%

Assay 98.0% ~ 102.0%

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