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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA
Name

Diosgenin

Other names DIOSGENIN

512-04-9

Nitogenin

UNII-K49P2K8WLX

(3beta,25R)-spirost-5-en-3-ol

CAS number 512-04-9
Molecular Formula C27H42O3
Molecular Weight 414.63

Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25.

A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including pregnenolone, progesterone.

It has a role as an apoptosis inducer, an antiviral agent, an antineoplastic agent, and a metabolite. It is a 3beta-sterol, a spiroketal, a hexacyclic triterpenoid, and a sapogenin. It derives from a hydride of a spirostan

Diosgenin is an important basic raw material for the production of steroidal hormone drugs . Steroid hormone has a strong anti-infective, anti-allergic, anti-virus and anti-shock pharmacological effects, the treatment of rheumatism, cardiovascular, lymphatic leukemia, cell encephalitis, skin diseases, anti-tumor and rescue of critically ill patients important treatment; it is important steroid hormone drug intermediates acetate pregnancy enolase raw materials, can be synthesized by its norethindrone, fluocinolone, and other steroid drugs.Diosgenin pharmaceutical industry is referred as "medicinal gold", medicinal value is very important and broad.

ASSAY PARAMETERS
SPECIFICATION
RESULTS
Part used
Stem
Complies
Appearance
White fine Powder
Complies
Odor
Characteristic
Complies
Taste
Characteristic
Complies
Particle size
100% pass 80 mesh sieve
Complies
Diosgenin (HPLC )
6%-98% min.
Complies
Loss on drying
5% max.
3.46%
Ash content
5% max.
2.38%
Heavy metals
≤10ppm
Complies
Total plate count
1000 cfu/g max.
Complies
E.coli
Negative
Complies
Salmonella
Negative
Complies
Yeast & mold
100 cfu/g max.
Complies

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