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Active Pharmaceuticals

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  • Specifications
  • Product Description
  • Product Usage
  • COA

Product Name: Dextromethorphan Hydrobromide
Synonyms: Delsym;Sisaal;Dextro;ROMILAR;medicon;tusilan;Tussade;antussan;metrorat;Dormetan;;Romilar;Tussade;
CAS No.: 125-69-9
EINECS No.:204-750-1
Molecular Formula: C18H26BrNO
Molecular Weight: 352.31
Appearance: white crystalline powder
Standard: Enterprise Standard

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines,including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp,Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found other uses inmedicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

1. Dextromethorphan hydrobromide is used to treat a dry (nonproductive) cough caused by colds, flu or inhaled irritants.

2. The primary use of dextromethorphan hydrobromide is as an antitussive, or cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications.

3. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well.

Test Items
Specification
Test Results
Appearance
white or almost white crystalline powder, slightly smelly
white crystalline powder
Melting point
123~127°C
123~125°C
Specific Rotation
+28°~+30°
+29°
Acidity(PH)
5.2~6.5
5.8~6.2
Water
4.0%~5.5%
5.0%
Residue On Ignition
Not more than 0.1%
Conforms
N.N - dimethylaniline
Comply with the standard
Conforms
Phenolic Compounds
Comply with the standard
Conforms
Related Substance
Comply with the standard
Conforms
Assay
Between99.0~102.0%
99.53%
Conclusion
This batch is complies with USP 34.

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