Synonyms: 11,12-dihydroxyprogesterone;11,21-Dihydroxypregn-4-ene-3,20-dione;11,21-Dihydroxyprogesterone;11-beta,21-Dihydroxypregn-3,20-dione;11-beta,21-dihydroxy-pregn-4-ene-20-dione;11-Hydroxycorticoaldosterone;17-Deoxycortisol;21-dihydroxy-20-dion(11-beta)-pregn-4-ene-11
CAS: 50-22-6
MF: C21H30O4
MW: 346.46
EINECS: 200-019-6
Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow.
Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.Biological Activity Endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.
