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Pharmaceutical Peptides

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Name PT-141
Other Name PT141 Acetate
CAS No. 189691-06-3
EINECS N/A
MF C50H68N14O10
MW 1025.18
Density 1.43
Purity 99% min
Usage Peptides; It is believed that it can improve both male and female sexual problems by increasing their sexual performance and desire in lovemaking.

PT-141 (Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction.The mechanism of action of PT-141 (Bremelanotide) may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.Clinical data indicates that PT-141 (Bremelanotide) may be effective in treating a broad range of patients suffering from ED.

The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is more patient-friendly than invasive treatments for ED, such as injections and trans-urethral pellets, and appears to result in a rapid onset of action.Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II).PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.

PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men and women. PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido.

PT-141 functions by activating the melanocortin 1 receptor and MC4R namely. Bremelanotide originally was tested for nasal spray delivery but was discontinued after concerns about side effects. Bremelanotide PT141, as Melanotan II, may cause spontaneous arousal enhancing effect. Unlike other supplements, PT 141 results do not act on the vascular body, but directly increases desires through the nervous system.

PT-141 or Bremelanotide is the generic term for a peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 has a similar structure to Melanotan-II and is a synthetic analogue of alpha-Melanocyte stimulating hormone (α-MSH). Alpha-MSH is an endogenous peptide that has potential influence over lipid metabolism, appetite, and sexual libido. PT-141 is a potential remedy for the treatment of sexual dysfunction and studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.

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