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Active Pharmaceuticals

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Name Avermectin
Synonyms Abamectin 100mg [71751-41-2];AbaMectin (AverMectin B1)(FDA);Purity of AbaMectin;AverMectin B1a-AverMectin B1b Mixt
Molecular Formula C49H74O14
Molecular Weight 887.11
CAS Registry Number 71751-41-2
EINECS Number 200-096-6
Melting point 150-155°C
Boiling point 717.52°C
Density 1.2±0.1 g/cm3

Abamectin was first developed by satoshi omura et al., kitasato university in Japan and Merck company in the United States as a class of 16-element macrolide compounds with insecticidal, acaricidal and nematoidal activities, produced by the fermentation of Streptomycesavermitilis in Streptomyces. There are 8 components in natural avermectin, mainly 4 of which are A1a, A2a, B1a and B2Chemicalbooka, with a total content ≥80%. The four corresponding homologues with smaller proportions are A1b, A2b, B1b and B2b, with a total content of less than 20%. At present, abamectin is used as the main insecticidal ingredient (AvermectinB1a+B1b, where B1a is not less than 90% and B1b is not more than 5%), and the content of B1a is calibrated.

1. Avermectin/Abamectin is the new type of anti-acarid antibiotic, which is distilled after microbial ferment,B1a is the most active content of it and has a very good effect on anti-acarid and other pests, so it has the feature of"broad-spectrum, high efficient, low hangover and easy use". So it is the ideal biological agricultural chemical to current anti-pest.

2. Avermectin/Abamectin to kill pest through eat (mastication insects and stick & suck insects) and touch(avm can enter into body through insects' stoma and claw), it blocks the nerval conduct system of insects to paralysis and dyed.

3. Avermectin/Abamectin can be decomposed by light and microbe, and can be absorbed into the body of plant by its roots, so it is safe to the environment.

TEST STANDARD RESULTS
Identification IR Corresponds with that of standard Conforms
HPLC The retention time for Bla corresponds with that of standard preparation Conforms
Appearance White to light yellow crystalline powder,Non-visible-exotic impurities Conforms
Loss on drying ≤2.0% 1.16
Acetone insolubles ≤0.2% 0.03%
Ph 4.5~7.0 6.05
B1a/B1b ≥4.0% 3.18
B1 ≥95% 97.97%
B1a ≥90% 96.52%

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