CAS: 330784-47-9
Character: White to Off-White Cyrstalline Solid.
Assay: 99% min.
Molecular Formula: C23H26ClN7O3
Molecular Weight: 483.9506
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Store: Store at room temperature away from moisture, heat, and light.
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA and EMA,it acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis and retina.Avanafil works the same way as the three other ED drugs currently on the market: Viagra, Cialis, and Levitra. All these drugs target an enzyme called PDE5,and avanafil appears to inhibit this enzyme more selectively than the other. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.Avanafil's most frequent side effect was headache, and the other common side effects included flushing and nasal congestion,this new drug may have fewer side effects.
Avanafil is used to treat male sexual function problems such as impotence or erectile dysfunction,it is in a class of medications called phosphodiesterase inhibitors.Avanafil works by increasing blood flow to the penis to help a man get and keep an erection.This drug does not protect against sexually transmitted diseases such as HIV, gonorrhea and syphilis.To decrease your risk of infection, always use an effective barrier method during all sexual activity.
Description |
White or Almost White Crystalline Powder |
white powder |
Identification |
A.B. |
Positive |
Assay |
97.0~103.0% |
99.0% |
Specific Rotation |
+101°~+105° |
+102.6° |
Loss On Drying |
1.0%max |
0.28% |
Organic Volatile Impurities |
meets the requirement. |
Conforms |
Related Substances |
meets the requirement. |
Conforms |
Residual Solvents |
meets the requirement. |
Conforms |
Particle Size |
100% ≤ 20 microns |
Conforms |