China Anabolic Steroids Powder Manufacturer
EnglishAfrikaansБългарскиNederlandsFrançaisDeutschItaliano日本語LatīnaNorskپارسیPolskiPortuguêsRomânăРусскийSlovenčinaSlovenščinaEspañolSvenskaTürkçeУкраїнськаудмурт кыл

Nootropics

» Pharmaceuticals » Nootropics

  • Specifications
  • Product Description
  • Product Usage
  • COA
Name Sunifiram
Systematic (IUPAC) name 1-benzoyl-4-propanoylpiperazine
CAS number 314728-85-3
Formula C14H18N2O2
Appearance white powder
Application a piperazine derived research chemical which has nootropic effects
Stock bulk in stock
Assay 99%

Sunifiram is one of the newest nootropics on the market showing very promising initial results. It falls into the ampakine family of nootropic supplements because it is an AMPA agonist.Some reviews have suggested that it works similarly to Piracetam but it is over 1000 times more potent than Piracetam for the same dosage.

Sunifiram is highly effective at boosting memory function as well as attention span, learning, decision making and alertness.A lot of initial reviews and user experiences suggest that Sunifiram could become one of the most popular nootropic study aids for improving concentration.

Sunifiram has a similar chemical structure to Piracetam but initial studies show that it is significantly more potent than this widely used racetam.Sunifiram so far shows very positive results as memory enhancer and it is currently being investigated for potential treatment of Alzheimer's and other diseases related to cognitive decline.

User reviews and Sunifiram logs point to the fact that this supplement makes information recall much easier and helps you think more clearly. Sunifiram is being compared to Noopept quite a bit because of their similar potency levels.Initial observations suggest that Sunifiram is better as a memory booster while Noopept might have an edge on increasing focus and alertness.

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232). This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation. This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

The exact mechanism to explain how Sunifiram is able to have such a strong cognitive benefit is yet to be found, but scientist have identified some interesting models to show how some of these attributes may be better understood. One such mechanism is that of NMDA signaling which was confirmed after Sunifiram dosages were maintained for over 7 days.

This can explain some of the NMDA-dependent Long Term Potentiation seen with Sunifiram use.Further studies have shown rodents with memory impairment (centered around the hippocampus) benefitted from Sunifiram administration, when their ability to complete training sessions was measured. Finally, Sunifiram injections were able to cause the release of acetylcholine, which was detected in the prefrontal cortex of laboratory mice.

For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.

Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associated with this class). Sunifiram has mechanisms similar to Nefiracetam in the hippocampus, and similar to that drug sunifiram shows anti-amnesiac properties and is potentially a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater than piracetam on a per weight basis, and preliminary evidence suggest it has a similarly low toxicity profile.

 

Item Specification Result
Appearance An odorless, almost white or buff colored powder pass
Solubility 1, Very slightly soluble in water pass
2, slightly soluble in alcohol pass
3, practically insoluble in most other organic solvents pass
4, disolves in diluted aqueous sodium hydroxide solutions Pass
Identification a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. pass
b)The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 4.0% 0.46%
[a]20/D
C=1 in 1M HCl/EtOH 1:4
+18 ~ +22o +20.9o
Assay(HPLC) Not less than 95.0% 99.18%
Levothyroxine sodium Not more than 5.0% 0.68%
Conclusion Up to the Standard for Export

Enquiry Form ( we will get back you as soon as possible )

Name:
*
Email:
*
Message:

Verification:
1 + 5 = ?

Maybe you like also

  • Our Advantage

    Good Price

    High Quality

    Fast Delivery

    Safe Shipment

    Excellent After-sale Service

  • Local Warehouse

    EU Warehouse

    UK Warehouse

    USA Warehouse

    Canada Warehouse

    Australia Warehouse

  • Payment Method

    Paypal

    Bitcoin

    Bank Wire

    Money Gram

    Western Union

  • Contact Us

    Email: jacob@steroid-peptide.com

    WhatsApp: +8615636286252

    Phone: 0086-15636286252

    Website: www.steroid-peptide.com

    Welcome your inquiry