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Finasteride
CAS: 98319-26-7
Assay: 99%
Appearance: White or off-white crystal powder
Molecular Formula: C23H36N2O2
Molecular Weight: 372.5441
Density: 1.066g/cm3
Boiling Point: 576.61°C at 760 mmHg
Flash Point: 177.448°C
Vapour Pressure: 0mmHg at 25°C
Usage: It is 5 alpha – reductase inhibitor that can inhibit testosterone to convert into DHT. Also used for the treatment of Hyperplasia of prostate. Finasteride is a 4– aza-steroid compound which is a specific inhibitor of the metabolism of testosterone within dihydro testosterone become stronger during the cell type-II enzyme 5a-reductase. The enlarged prostate called benign prostatic hyperplasia or prostate depends on the conversion of testosterone to dihydrotestosterone.

Finasteride is a popular anti-androgen medication manufactured by Merck most commonly known as either Proscar or Propecia. Based on the progesterone skeleton, Finasteride belongs to a class of medications known as 5alpha-reductase inhibitors and as such is used for the treatment revolving around type 2 5-AR based occurrences.

This is important for performance enhancers as DHT based anabolic steroids have specific side-effects that may occur that can largely be remedied with the use of a 5-AR inhibitor such as Finasteride. As a type 2 5-AR inhibitor Finasteride was designed for the purpose of treating hair-loss, prostate enlargement, as well as prostate cancer.

Finasteride is very common among those who supplement with anabolic steroids yet fear hair-loss but there are important things you need to understand before you consider Finasteride use. As an androgen suppressor Finasteride can seriously inhibit the gains made while on cycle, severely and on that basis it is not highly recommended for on-cycle hair preservation.

Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) in men. Oral use though will reduce DHT levels systemically, which may adversely affect training and sex drive.

It is also used in combination with doxazosin in the treatment of benign prostatic hyperplasia (BPH).] Finasteride is an orally active testosterone Type II 5-alpha reductase inhibitor, inhibiting the enzyme that converts testosterone to dihydrotestosterone (DHT).

Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually reverse loss moderately.

For use in cycles with testosterone, I don't think it is bad at all. One simply doesn't want less DHT than normal. As the amount of testosterone in the system increases, the amount of finasteride needed to keep levels down to normal increases. I consider 5 mg/day reasonable at the gram per week level, and proportionally less at lower dosages of testosterone.

 

Specific rotation -56°~-60° -58.2°
Identification IR Matches with working standard Complies
HPLC
Solubility Freely soluble in chloroform and in alcohol; Very slightly soluble in water Conform
Heavy metals ≤10ppm <10ppm
Water ≤0.3% 0.22%
Residue on ignition ≤0.1% 0.05%
Relative material Max impurity≤0.5% 0.36%
Total impurity≤1.0% 0.52%
Assay 98.5~101.0% 99.48%

 

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