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Active Pharmaceuticals

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  • Product Description
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  • COA
Product name Deflazacort
Other name Deflazacort Intermediate; Deflazacort;21-Deacetoxy Deflazacort
CAS register number 14484-47-0
EINECS 238-483-7
Molecular formula C25H31NO6
Molecular weight 441.52
Melting point 255-256.5°C
Assay 98%

Deflazacort is a steroid that reduces inflammation in the body. Deflazacort is used to treat Duchenne muscular dystrophy in adults and children who are at least 5 years old. Deflazacort is not a cure for muscular dystrophy, butdeflazacort may improve muscle strength and slow the progression of disability.

It has anti-inflammatory and anti-allergic effects and is used in adrenal cortex hypofunction, autoimmune diseases, allergic diseases and hematological diseases.

Product name Deflazacort
Appearance White crystalline powder
Chromatographic purity Any individual impurity not more than 1.0%

Total impurities not more than 2.0%

 0.4%

1.3%
Loss on drying Not more than 0.5% 0.2%
Residue on ignition Not more than 0.2% 0.03%
Residual solvents Methanol≤3000ppm

Methylene Chloride≤600ppm

Chloroform≤60ppm

Tetrahydrofuran≤720ppm

 370ppm

Not detect out

Not detect out

Not detect out
Assay Between 97.0% and 102.0% 99.3%
Micronixation 90% not more than 10 microns 90% not more than 10

aicrons

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