9-Fluorenol CAS:1689-64-1

Raw Hydrafinil (9-Fluorenol) powder (1689-64-1) is an alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. Hydroxyfluorene can be converted to fluorenone by oxidation.

At same time, Raw Hydrafinil (9-Fluorenol) powder is a wakefulness-promoting agent, countering sleepiness and inattention. It’s an analogue and pro-drug of modafinil (also known as Provigil) – a compound used by Airforce pilots on long missions to stay awake and alert. Hydrafinil (aka 9-Fluorenol) is also a novel eugeroic nootropic that is very similar in action to Modafinil. It was originally developed as a research compound to promote wakefulness and alertness. Due to its reported efficacy as a eugeroic agent, it is becoming popular among advanced nootropics users. Interestingly, users report less stimulating effects than Modafinil, but a greater ability to promote vigilance. Other reported benefits include attentional enhancement, increased motivation, subtle mood boost, improved cognitive function and ability to learn.

1.Dopamine reuptake inhibitor
An increase in dopamine production is known to improve cognition. Hydrafinil plays a role as a dopamine reuptake inhibitor, increasing dopamine concentrations.5-HT6 antagonist: Antagonism of 5-HT6 receptor can result to increase in norepinephrine and dopamine concentrations in the prefrontal cortex, as well as increasing the production of choline and glutamate in different parts of the brain. Makers of Hydrafinil theorize that it functions as a 5-HT6 receptor antagonist.
2.Increase Glutamate levels
As mentioned earlier, antagonism of 5-HT6 receptors increases the production of glutamate in the brain. This could lead to enhanced memory and learning process. There is a great possibility that Hydrafinil's function as a 5-HT6 receptor antagonist could result in the improvement of cognitive performance.
3.Increase Norepinephrine levels
Manufacturers of Hydrafinil claim that it increases norepinephrine levels specifically in the prefrontal cortex by antagonizing 5-HT6 receptor. Increase in concentrations of norepinephrine could result to improvement of cognition. However, there's no enough evidence to prove this theory.
4.Increase Histamine levels
Hydrafinil is known to enhance histamine levels in the hypothalamus. Histamine plays an important role in normalizing our circadian rhythm and regulating sleep-wake cycles.